2-Bromopropionic Acid: A Crucial Synthesis Intermediate for Agrochemicals and Pharmaceuticals

Introduction:

2-Bromopropionic acid, identified by the CAS number 598-72-1, stands as a versatile chemical employed extensively as an intermediate in organic synthesis. Renowned for its contributions to herbicide and pharmaceutical production, it holds significant industrial importance.

Chemical Properties:

With a molecular formula of C3H5BrO2  and a molar mass of 152.97 g/mol, 2-bromopropionic acid showcases a density of 1.7 g/mL at 25°C. It exhibits a melting point of 25.7°C and a boiling point of 203°C. A flash point of 212°F signals its potential to form ignitable mixtures in air upon vaporization.

Physical Appearance:

When transitioning from solid to liquid, 2-bromopropionic acid assumes a clear colorless to yellow state, a transformation crucial for its utilization in various synthesis processes.

Storage and Handling:

To ensure optimal stability, 2-bromopropionic acid should be stored at room temperature in a well-ventilated, dry environment. It must be segregated from oxidants, alkalis, and food raw materials to prevent hazardous reactions or contamination.

Applications:

The versatility of 2-bromopropionic acid is evident in its role as an intermediate in synthesizing a diverse array of products, including herbicides like quizaloxazole, oxazolaproxyl, and thiazolaproxyl, along with fungicides such as metalaxyl and benzoxyl. Additionally, it contributes to the synthesis of pharmaceutical intermediates and synthetic amino acids like alanine.

Conclusion:

2-Bromopropionic acid's pivotal role as an intermediate in the synthesis of agrochemicals and pharmaceuticals underscores its significance in chemical industries. Its broad application spectrum and the necessity for careful handling highlight its indispensable position in the synthesis of complex molecules, driving innovation and progress in various sectors.