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2-Chloromandelic Acid: A Crucial Component in Drug Development

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2-Chloromandelic Acid: A Crucial Component in Drug Development

Introduction:

2-Chloromandelic acid, with its distinctive CAS number 10421-85-9, occupies a central position as a pharmaceutical intermediate. Renowned for its role in synthesizing Clopidogrel, a vital anticoagulant, it also serves as a fundamental reagent in organic chemistry endeavors.

Chemical Profile:

With a molecular formula of C8H7ClO3 and a molar mass of 186.59 g/mol, 2-Chloromandelic acid exhibits a density of approximately 1.3245 g/cm³. Its melting point, typically within the range of 90-93°C (lit.), precedes a boiling point estimated at 266.91°C. A flash point of 165.7°C signals its vaporization potential, crucial for safe handling.

Physical Attributes:

Manifesting as white to yellowish lenses, 2-Chloromandelic acid showcases its purity and quality, essential for precise synthetic applications.

Storage and Safety:

To ensure stability, this compound demands storage in dark, sealed containers at room temperature. Due to its irritant and corrosive properties, cautious handling with appropriate protective gear such as gloves and goggles is imperative.

Applications:

The versatility of 2-Chloromandelic acid finds expression in its pivotal role as a building block for various pharmaceuticals. Notably, its contribution to the synthesis of Clopidogrel underscores its significance in advancing medical treatment modalities.

Conclusion:

In essence, 2-Chloromandelic acid emerges as an indispensable asset in pharmaceutical research and drug development. Its profound impact on synthesizing life-saving medications epitomizes its pivotal role in the realm of health sciences, shaping a future where innovative treatments enhance global well-being.


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