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2-(4-Chlorobenzoyl) Benzoic Acid CAS 85-56-3

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2-Carboxy-4-chlorobenzophenone is used as pharmaceutical, dye intermediates, for the production of chlorthalidone, 2-chloroanthraquinone, etc
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Product Description


2-(4-Chlorobenzoyl) Benzoic Acid, also known by its synonyms 2-Carboxy-4-chlorobenzophenone and CBB, is a key intermediate compound widely used in the pharmaceutical and dye industries. With the molecular formula C14H9ClO3 and a molecular weight of 260.67, it plays an essential role in the production of significant chemical products, such as Chlorothiazide, 2-Chloroanthraquinone, and other related compounds.

This compound exists as a white or light yellow crystalline solid with excellent stability, making it ideal for use in various industrial applications. Its versatility extends across pharmaceutical synthesis, particularly in the production of diuretic drugs like chlorthalidone, and in dye manufacturing, where it serves as a precursor for anthraquinone-based dyes.


Product Name 2-(4-Chlorobenzoyl) Benzoic Acid
Synonyms 2-Carboxy-4-chlorobenzophenone; 2-(4-chlorobenzoyl)-benzoic acid; 2-(4-Chlorobenzoyl) benzoic acid; 4'-Chlorobenzophenone-2-carboxylic acid; CBB
Molecular Formula C14H9ClO3
Molecular Weight 260.6725
CAS Registry Number 85-56-3
Molecular Structure 2-(4-Chlorobenzoyl) Benzoic Acid_149_103
Product Application Used as a pharmaceutical and dye intermediate for the production of Chlorothiazide, 2-Chloroanthraquinone, etc.



Chemical Properties

2-(4-Chlorobenzoyl) Benzoic Acid is a solid chemical with the following distinctive properties:

  • Appearance: White or light yellow crystalline substance

  • Density: 1.357±0.06 g/cm³

  • Melting Point: 149-150°C, ensuring its solid form remains stable at moderate temperatures.

  • Boiling Point: 470.8±30.0°C, indicating its ability to withstand high temperatures before vaporization.

  • Flash Point: 238.5°C, suggesting that it is relatively safe under normal conditions but requires caution under high heat.

This compound is known for its excellent stability and relatively low toxicity, though it can be irritating to the skin and eyes. It should be handled with appropriate safety precautions.


Product Advantages


  • Versatile Applications: 2-(4-Chlorobenzoyl) Benzoic Acid is a key intermediate in the production of pharmaceuticals and dyes, making it highly valuable across multiple industries.

  • Stable and Reliable: With a high melting point and boiling point, this chemical ensures excellent thermal stability during storage and processing.

  • Cost-Effective: By serving as a precursor for the synthesis of important compounds, it reduces production costs for pharmaceutical and dye industries.

  • Efficient Catalyst: The compound can also be used as a catalyst in the oxidation of aromatic compounds, further enhancing its utility in various chemical reactions.


Production Usage


2-(4-Chlorobenzoyl) Benzoic Acid is primarily used as an intermediate in both the pharmaceutical and dye industries. In pharmaceutical applications, it plays a critical role in producing Chlorthalidone, a diuretic drug that helps manage high blood pressure and edema. It also acts as a vital precursor in the production of 2-Chloroanthraquinone, a compound used in anthraquinone-based dyes like alizarin and indanthrene.

In addition to its medicinal uses, this compound is also employed in the oxidation of aromatic compounds, aiding in various organic synthesis processes.


Safety and Storage


It should be stored in a sealed, dry, and room temperature condition. 

It should be kept away from heat, fire, and oxidizing agents. 

It has low toxicity but high irritation, and can cause skin and eye damage. 

It should be handled with care and protective equipment.


FAQs


  1. What are the primary applications of 2-(4-Chlorobenzoyl) Benzoic Acid?

    • It is primarily used in pharmaceutical synthesis for producing chlorthalidone and in dye manufacturing as a precursor to anthraquinone dyes.

  2. Is 2-(4-Chlorobenzoyl) Benzoic Acid toxic?

    • It has low toxicity but can cause irritation to the skin and eyes. Protective gear should be used during handling.

  3. How should 2-(4-Chlorobenzoyl) Benzoic Acid be stored?

    • It should be stored in a sealed, dry environment at room temperature, away from heat and oxidizing agents.

  4. Can 2-(4-Chlorobenzoyl) Benzoic Acid be used in industrial applications?

    • Yes, it is widely used in both the pharmaceutical and dye industries, with applications in organic synthesis as a catalyst and intermediate.

  5. What precautions should be taken when handling this chemical?

    • Ensure proper protective equipment is worn, including gloves, goggles, and gas masks. Follow strict safety protocols to avoid exposure to irritants.

For more information and other intermediates, visit our Intermediates page.


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