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2-Chloromandelic Acid CAS 10421-85-9

2-Chloromandelic Acid is used as a pharmaceutical intermediate,general reagent, organic synthesis,Clopidogel intermediate.
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Product Name 2-Chloromandelic Acid
Synonyms (+/-)-2-Chloromandelic acid; 2-Chloro-alpha-hydroxybenzeneacetic acid; 2-chloro mandelic acid; DL-2-Chloromandelic acid; (2-chlorophenyl)(hydroxy)acetic acid; (2S)-(2-chlorophenyl)(hydroxy)ethanoate; (2R)-(2-chlorophenyl)(hydroxy)ethanoate; DL-Chloro phenyl glycollic acid
Molecular Formula C8H7ClO3
Molecular Weight 186.59478
CAS Registry Number 10421-85-9
Molecular Structure 2-Chloromandelic Acid_160_160
Product Application It serves as a crucial intermediate in organic synthesis, extensively employed in the production of chemicals such as dyes, pharmaceuticals, and pesticides. It also functions as a catalyst and polymer additive.


Names and Identifiers

2-Chloromandelic acid, recognized by the CAS number 10421-85-9, it adopts various synonyms,

including o-chloromandelic acid and DL-2-Chloromandelic acid, indicative of its structural configuration.

With a molecular formula of C8H7ClO3 and a molar mass of 186.59 g/mol.

Chemical Properties

2-Chloromandelic acid manifests as a white to yellowish crystalline substance exuding a pale cream hue. 

It boasts a melting point of 90-93°C and a boiling point approximately reaching 266.91°C. 

The compound's flash point registers at 165.7°C, signifying the temperature at which it can vaporize to engender an ignitable mixture in air.

In terms of physical attributes, 2-Chloromandelic acid exhibits a density of approximately 1.3245 g/cm³.

Storage and safety

For optimal preservation of its stability and efficacy, storage in a dark and dry environment at room temperature is recommended.

Production Usage

It is a versatile chemical compound utilized primarily as a pharmaceutical intermediate, notably contributes to the synthesis of Clopidogrel, a medication pivotal in preventing blood clots. 

Serving as a pivotal reagent in organic synthesis, 2-Chloromandelic acid assumes a crucial role in the production of various pharmaceuticals. 

Its stability coupled with its reactive nature renders it a valuable constituent in the development of novel drugs and treatments, thereby significantly advancing medical science and healthcare.


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