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Methyl Acetoacetate CAS 105-45-3

methyl acetoacetate is an intermediate of fungicides hymmezol, dimethylsulfurol, ethylsulfurol, insecticides diazinon, pyrifos, pyrimidine oxyphosphorus, herbicide imidazoleetinic acid, rodenticide, rodenticide, rodenticide, rodenticide, rodenticide, etc.
It is used as a solvent for cellulose ether and a mixed solvent for cellulose resin, and is also used in organic synthesis such as pesticides, medicines, dyes, and polymer stabilizers.
Used in pharmaceutical industry
organic synthesis. Solvent.
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Product Name Methyl Acetoacetate
Synonyms

Methyl acetoacetaten; Acetoacetic acid methyl ester; Butanoic acid, 3-oxo-, methyl ester:; methyl 3-oxobutanoate; MAA

Molecular Formula C5H8O3
Molecular Weight 116.1152
CAS Registry Number 105-45-3
Molecular Structure Methyl Acetoacetate_90_40
Product Application used in the pharmaceutical industry


Names and Identifiers

Methyl acetoacetate, also known as MAA or acetoacetic acid methyl ester, is identified by CAS number 105-45-3,

and has a molecular formula of C5H8O3 with a molar mass of 116.12 g/mol. 

Chemical Properties

This colorless transparent liquid possesses an aromatic flavor, with a density of 1.076 g/mL at 25°C and a melting point of -80°C. 

Boiling occurs at 171.7°C, and it exhibits miscibility with ethanol and ether while being slightly soluble in water. 


Production Usage


Methyl acetoacetate serves as a vital intermediate in organic synthesis, particularly for fungicides like hymmezol and dimethylsulfurol, as well as insecticides such as diazinon and pyrifos. 

It finds application as a solvent for cellulose ether and a mixed solvent for cellulose resin, along with usage in pharmaceuticals, pesticides, dyes, and polymer stabilizers. 

Safety and Storage

Despite being less toxic, precautions should be taken during handling, with operators wearing protective equipment due to its moderate irritant and anesthetic properties.

Storage in well-sealed containers in cool, ventilated areas is recommended, adhering to regulations for flammable and toxic chemicals. 

Methyl acetoacetate's versatility and relatively low toxicity make it a valuable component in various industrial processes.

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